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January 01, 2009

Secondary Causes of Hypertension

Diseases
  • Chronic kidney disease
  • Cushing’s syndrome
  • Coarctation of the aorta
  • Obstructive sleep apnea
  • Parathyroid disease
  • Pheochromocytoma
  • Primary aldosteronism
  • Renovascular disease
  • Thyroid disease

Drugs Associated with Hypertension in Humans

  • Prescription drugs
  • Adrenal steroids (e.g., prednisone, fludrocortisone, triamcinolone)
  • Amphetamines/anorexiants (e.g., phendimetrazine, phentermine, sibutramine)
  • Antivascular endothelin growth factor agents (bevacizumab, sorafenib, sunitinib), estrogens (usually oral contraceptives)
  • Calcineurin inhibitors (cyclosporine and tracolimus)
  • Decongestants (phenylpropanolamine and analogs)
  • Erythropoiesis stimulating agents (erythropoietin and darbepoietin)
  • Nonsteroidal antiinflammatory drugs, cyclooxygenase-2 inhibitors
  • Others: venlafaxine, bromocriptine, bupropion, buspirone, carbamazepine, clozapine, desulfrane, ketamine, metoclopramide
  • Situations: β-blocker or centrally acting α-agonists (when abruptly discontinued); β-blocker without α- blocker first when treating pheochromocytoma

Food substances

  • Sodium
  • Ethanol
  • Licorice
  • Tyramine-containing foods if taking a monoamine oxidase inhibitor

3 comments:

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Rx Pharmacy July 7, 2009 2:58 PM  

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